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Best peptides for weight loss
Best peptides for weight loss: what each compound does, and which vendors sell it pure. Weight-loss peptides are not interchangeable. Single-agonist GLP-1s, dual GLP-1/GIP agonists and triple agonists differ in how much weight they move, how well they are tolerated and what they cost per milligram. Every peptide below is ranked by independent purity testing and live vendor pricing.
Written by Jian Wang, Founder & CEO
Every weight-loss peptide we track, compared
| Peptide | Purity (avg / 10) | Lab tests | Vendors | Best price | |
|---|---|---|---|---|---|
| Retatrutide Triple agonist — the next-generation weight-loss compound. | C7.79 | 4565 | 412 | $1.50 / mg | Compare vendors |
| Tesamorelin GHRH analogue with the strongest human data on visceral fat. | E5.74 | 723 | 144 | $2.15 / mg | Compare vendors |
| Cagrilintide Amylin analogue — usually studied alongside a GLP-1, not instead of one. | D6.03 | 203 | 66 | $4.85 / mg | Compare vendors |
| Tirzepatide Dual GLP-1/GIP agonist — the most-tested weight-loss peptide we track. | C7.96 | 2825 | 279 | $1.13 / mg | Compare vendors |
| Semaglutide The original GLP-1 — appetite suppression and steady fat loss. | C7.34 | 382 | 83 | $2.00 / mg | Compare vendors |
| Mazdutide GLP-1/glucagon dual agonist studied for weight and metabolic health. | A9.07 | 29 | 16 | $4.00 / mg | Compare vendors |
| Survodutide GLP-1/glucagon agonist — an emerging weight-loss candidate. | E5.86 | 27 | 9 | $6.00 / mg | Compare vendors |
Purity is the mean lab score across every vendor we have tested for that peptide, out of 10. Most vendors score in the 9s, so the number separates them where the letter grade does not. Prices update as catalogs are re-scraped.
Where to buy each one
GHRH analogue with the strongest human data on visceral fat.
144 vendors · 723 lab tests
Amylin analogue — usually studied alongside a GLP-1, not instead of one.
66 vendors · 203 lab tests
Dual GLP-1/GIP agonist — the most-tested weight-loss peptide we track.
279 vendors · 2825 lab tests
The original GLP-1 — appetite suppression and steady fat loss.
83 vendors · 382 lab tests
GLP-1/glucagon dual agonist studied for weight and metabolic health.
16 vendors · 29 lab tests
How this ranking is put together
Nothing on this page is a recommendation to take anything. It is a ranking of what independent labs found inside the vial, and what each vendor charges for it.
- 1
Start with the source record
Check the sample source, batch and test date on each published record. Sampling methods vary, and a result applies to the sample tested.
- 2
An independent lab runs them
Third-party HPLC and mass-spec testing measures what is actually in the vial against what the label claims.
- 3
Every result is published
Pass or fail, the certificate is linked from the vendor's page. The purity grade above is the average across all of them.
- 4
Prices are tracked separately
Vendor catalogs are re-scraped on a schedule and normalised to price per milligram, so multipacks and vial sizes compare honestly.
Common questions
- Which weight-loss peptide has the most vendor coverage?
- Retatrutide, carried by 412 vendors in our index with 4565 published lab tests. Wider coverage means more price competition, not that it is the right compound for you.
- What do weight-loss peptides cost?
- Prices are compared per milligram so vial sizes and multipacks are directly comparable. The cheapest verified listing in this category is currently $1.50 / mg for Retatrutide. Live prices are on each peptide's page.
- How do you decide which peptides belong in this category?
- A peptide appears here when published research studies it for this outcome. Peptides often belong to several categories — a compound studied for wound healing may also appear under skin or gut health. In this category that includes Retatrutide, Tesamorelin, Cagrilintide.
- Is Peptide Vendor Reviews selling these peptides?
- No. We do not sell peptides. We buy samples, publish independent lab results, and track vendor prices. Some vendor links are affiliate links, which never affects a purity score or a ranking position.